Does RASBURICASE Cause Ascites? 8 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 8 reports of Ascites have been filed in association with RASBURICASE (Elitek). This represents 0.9% of all adverse event reports for RASBURICASE.
8
Reports of Ascites with RASBURICASE
0.9%
of all RASBURICASE reports
5
Deaths
5
Hospitalizations
How Dangerous Is Ascites From RASBURICASE?
Of the 8 reports, 5 (62.5%) resulted in death, 5 (62.5%) required hospitalization, and 3 (37.5%) were considered life-threatening.
Is Ascites Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RASBURICASE. However, 8 reports have been filed with the FAERS database.
What Other Side Effects Does RASBURICASE Cause?
Tumour lysis syndrome (116)
Methaemoglobinaemia (92)
Off label use (90)
Product use in unapproved indication (76)
Bacterial infection (75)
Fungal infection (73)
Cellulitis (72)
Clostridium difficile colitis (72)
Lymphoid tissue hypoplasia (72)
Lymphopenia (72)
What Other Drugs Cause Ascites?
BEVACIZUMAB (1,067)
RIBAVIRIN (1,025)
TREPROSTINIL (672)
ACETAMINOPHEN (599)
SOFOSBUVIR (598)
PACLITAXEL (581)
LETROZOLE (579)
CYCLOPHOSPHAMIDE (561)
OXALIPLATIN (533)
METHOTREXATE (521)
Which RASBURICASE Alternatives Have Lower Ascites Risk?
RASBURICASE vs RAVULIZUMAB
RASBURICASE vs RAVULIZUMAB-CWVZ
RASBURICASE vs REBAMIPIDE
RASBURICASE vs REBETOL
RASBURICASE vs REBIF