Does RASBURICASE Cause Lymphopenia? 72 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 72 reports of Lymphopenia have been filed in association with RASBURICASE (Elitek). This represents 8.1% of all adverse event reports for RASBURICASE.
72
Reports of Lymphopenia with RASBURICASE
8.1%
of all RASBURICASE reports
6
Deaths
72
Hospitalizations
How Dangerous Is Lymphopenia From RASBURICASE?
Of the 72 reports, 6 (8.3%) resulted in death, 72 (100.0%) required hospitalization.
Is Lymphopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RASBURICASE. However, 72 reports have been filed with the FAERS database.
What Other Side Effects Does RASBURICASE Cause?
Tumour lysis syndrome (116)
Methaemoglobinaemia (92)
Off label use (90)
Product use in unapproved indication (76)
Bacterial infection (75)
Fungal infection (73)
Cellulitis (72)
Clostridium difficile colitis (72)
Lymphoid tissue hypoplasia (72)
Drug ineffective (71)
What Other Drugs Cause Lymphopenia?
FINGOLIMOD (1,515)
CYCLOPHOSPHAMIDE (952)
RITUXIMAB (932)
DEXAMETHASONE (814)
PREDNISONE (788)
DIMETHYL (598)
METHOTREXATE (549)
PREDNISOLONE (465)
TACROLIMUS (456)
MYCOPHENOLATE MOFETIL (453)
Which RASBURICASE Alternatives Have Lower Lymphopenia Risk?
RASBURICASE vs RAVULIZUMAB
RASBURICASE vs RAVULIZUMAB-CWVZ
RASBURICASE vs REBAMIPIDE
RASBURICASE vs REBETOL
RASBURICASE vs REBIF