Does RASBURICASE Cause Clostridium difficile colitis? 72 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 72 reports of Clostridium difficile colitis have been filed in association with RASBURICASE (Elitek). This represents 8.1% of all adverse event reports for RASBURICASE.
72
Reports of Clostridium difficile colitis with RASBURICASE
8.1%
of all RASBURICASE reports
6
Deaths
72
Hospitalizations
How Dangerous Is Clostridium difficile colitis From RASBURICASE?
Of the 72 reports, 6 (8.3%) resulted in death, 72 (100.0%) required hospitalization.
Is Clostridium difficile colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RASBURICASE. However, 72 reports have been filed with the FAERS database.
What Other Side Effects Does RASBURICASE Cause?
Tumour lysis syndrome (116)
Methaemoglobinaemia (92)
Off label use (90)
Product use in unapproved indication (76)
Bacterial infection (75)
Fungal infection (73)
Cellulitis (72)
Lymphoid tissue hypoplasia (72)
Lymphopenia (72)
Drug ineffective (71)
What Other Drugs Cause Clostridium difficile colitis?
CYCLOPHOSPHAMIDE (717)
PREDNISONE (619)
DEXAMETHASONE (575)
METHOTREXATE (562)
ETOPOSIDE (503)
CYTARABINE (489)
VINCRISTINE (482)
LENALIDOMIDE (388)
METHYLPREDNISOLONE (385)
CIPROFLOXACIN (378)
Which RASBURICASE Alternatives Have Lower Clostridium difficile colitis Risk?
RASBURICASE vs RAVULIZUMAB
RASBURICASE vs RAVULIZUMAB-CWVZ
RASBURICASE vs REBAMIPIDE
RASBURICASE vs REBETOL
RASBURICASE vs REBIF