Does METHOTREXATE Cause Lymphopenia? 549 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 549 reports of Lymphopenia have been filed in association with METHOTREXATE (Methotrexate). This represents 0.2% of all adverse event reports for METHOTREXATE.
549
Reports of Lymphopenia with METHOTREXATE
0.2%
of all METHOTREXATE reports
128
Deaths
243
Hospitalizations
How Dangerous Is Lymphopenia From METHOTREXATE?
Of the 549 reports, 128 (23.3%) resulted in death, 243 (44.3%) required hospitalization, and 57 (10.4%) were considered life-threatening.
Is Lymphopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 549 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Lymphopenia?
FINGOLIMOD (1,515)
CYCLOPHOSPHAMIDE (952)
RITUXIMAB (932)
DEXAMETHASONE (814)
PREDNISONE (788)
DIMETHYL (598)
PREDNISOLONE (465)
TACROLIMUS (456)
MYCOPHENOLATE MOFETIL (453)
VINCRISTINE (452)
Which METHOTREXATE Alternatives Have Lower Lymphopenia Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA