Does REGORAFENIB Cause Constipation? 349 Reports in FDA Database

Q: Does REGORAFENIB cause Constipation?

349 reports of Constipation have been filed with the FDA for REGORAFENIB, representing 3.7% of all REGORAFENIB adverse event reports.

Q: How dangerous is Constipation from REGORAFENIB?

Of 349 reports, 27 (7.7%) resulted in death and 150 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 349 reports of Constipation have been filed in association with REGORAFENIB (Stivarga). This represents 3.7% of all adverse event reports for REGORAFENIB.

349

Reports of Constipation with REGORAFENIB

3.7%

of all REGORAFENIB reports

Deaths

150

Hospitalizations

How Dangerous Is Constipation From REGORAFENIB?

Of the 349 reports, 27 (7.7%) resulted in death, 150 (43.0%) required hospitalization.

Is Constipation Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for REGORAFENIB. However, 349 reports have been filed with the FAERS database.

What Other Side Effects Does REGORAFENIB Cause?

Off label use (1,906) Fatigue (1,530) Palmar-plantar erythrodysaesthesia syndrome (1,230) Diarrhoea (1,221) Decreased appetite (941) Asthenia (825) Death (813) Dysphonia (702) Nausea (688) Pain in extremity (686)

What Other Drugs Cause Constipation?

LENALIDOMIDE (9,635) NIRAPARIB (4,128) ADALIMUMAB (4,063) SEMAGLUTIDE (4,036) TIRZEPATIDE (3,417) ERENUMAB-AOOE (3,104) MORPHINE (2,979) OXYCODONE (2,747) PALBOCICLIB (2,705) POMALIDOMIDE (2,374)

Which REGORAFENIB Alternatives Have Lower Constipation Risk?

REGORAFENIB vs REGORAFENIB\REGORAFENIB REGORAFENIB vs RELATLIMAB REGORAFENIB vs RELPAX REGORAFENIB vs RELUGOLIX REGORAFENIB vs REMDESIVIR

REGORAFENIB Full Profile All Constipation Reports All Drugs Causing Constipation REGORAFENIB Demographics