Does RITUXIMAB Cause Cholestasis? 210 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 210 reports of Cholestasis have been filed in association with RITUXIMAB (Rituxan). This represents 0.1% of all adverse event reports for RITUXIMAB.
210
Reports of Cholestasis with RITUXIMAB
0.1%
of all RITUXIMAB reports
36
Deaths
133
Hospitalizations
How Dangerous Is Cholestasis From RITUXIMAB?
Of the 210 reports, 36 (17.1%) resulted in death, 133 (63.3%) required hospitalization, and 18 (8.6%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RITUXIMAB. However, 210 reports have been filed with the FAERS database.
What Other Side Effects Does RITUXIMAB Cause?
Off label use (39,751)
Drug ineffective (32,186)
Rheumatoid arthritis (19,850)
Pain (16,675)
Fatigue (15,602)
Arthralgia (12,529)
Rash (12,102)
Drug intolerance (11,876)
Infusion related reaction (11,871)
Joint swelling (11,170)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which RITUXIMAB Alternatives Have Lower Cholestasis Risk?
RITUXIMAB vs RITUXIMAB-ABBS
RITUXIMAB vs RITUXIMAB-ARRX
RITUXIMAB vs RITUXIMAB-PVVR
RITUXIMAB vs RIVAROXABAN
RITUXIMAB vs RIVASTIGMINE