Does RUXOLITINIB Cause Bone marrow failure? 164 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 164 reports of Bone marrow failure have been filed in association with RUXOLITINIB (OPZELURA). This represents 0.2% of all adverse event reports for RUXOLITINIB.
164
Reports of Bone marrow failure with RUXOLITINIB
0.2%
of all RUXOLITINIB reports
40
Deaths
52
Hospitalizations
How Dangerous Is Bone marrow failure From RUXOLITINIB?
Of the 164 reports, 40 (24.4%) resulted in death, 52 (31.7%) required hospitalization, and 18 (11.0%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RUXOLITINIB. However, 164 reports have been filed with the FAERS database.
What Other Side Effects Does RUXOLITINIB Cause?
Off label use (12,492)
Death (6,561)
Fatigue (5,663)
Anaemia (3,593)
Haemoglobin decreased (3,297)
Platelet count decreased (3,028)
Diarrhoea (2,531)
Asthenia (2,529)
Dizziness (2,398)
Pneumonia (2,343)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which RUXOLITINIB Alternatives Have Lower Bone marrow failure Risk?
RUXOLITINIB vs SABRIL
RUXOLITINIB vs SACCHAROMYCES CEREVISIAE
RUXOLITINIB vs SACITUZUMAB GOVITECAN
RUXOLITINIB vs SACITUZUMAB GOVITECAN-HZIY
RUXOLITINIB vs SACROSIDASE