Does RUXOLITINIB Cause Hepatitis? 83 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 83 reports of Hepatitis have been filed in association with RUXOLITINIB (OPZELURA). This represents 0.1% of all adverse event reports for RUXOLITINIB.
83
Reports of Hepatitis with RUXOLITINIB
0.1%
of all RUXOLITINIB reports
12
Deaths
22
Hospitalizations
How Dangerous Is Hepatitis From RUXOLITINIB?
Of the 83 reports, 12 (14.5%) resulted in death, 22 (26.5%) required hospitalization, and 6 (7.2%) were considered life-threatening.
Is Hepatitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RUXOLITINIB. However, 83 reports have been filed with the FAERS database.
What Other Side Effects Does RUXOLITINIB Cause?
Off label use (12,492)
Death (6,561)
Fatigue (5,663)
Anaemia (3,593)
Haemoglobin decreased (3,297)
Platelet count decreased (3,028)
Diarrhoea (2,531)
Asthenia (2,529)
Dizziness (2,398)
Pneumonia (2,343)
What Other Drugs Cause Hepatitis?
METHOTREXATE (1,835)
ACETAMINOPHEN (1,450)
TOCILIZUMAB (1,184)
HYDROXYCHLOROQUINE (1,133)
ADALIMUMAB (1,096)
RITUXIMAB (1,017)
ETANERCEPT (1,013)
LEFLUNOMIDE (997)
PEMBROLIZUMAB (935)
NIVOLUMAB (930)
Which RUXOLITINIB Alternatives Have Lower Hepatitis Risk?
RUXOLITINIB vs SABRIL
RUXOLITINIB vs SACCHAROMYCES CEREVISIAE
RUXOLITINIB vs SACITUZUMAB GOVITECAN
RUXOLITINIB vs SACITUZUMAB GOVITECAN-HZIY
RUXOLITINIB vs SACROSIDASE