Does SELINEXOR Cause Constipation? 390 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 390 reports of Constipation have been filed in association with SELINEXOR (XPOVIO). This represents 5.2% of all adverse event reports for SELINEXOR.
390
Reports of Constipation with SELINEXOR
5.2%
of all SELINEXOR reports
39
Deaths
90
Hospitalizations
How Dangerous Is Constipation From SELINEXOR?
Of the 390 reports, 39 (10.0%) resulted in death, 90 (23.1%) required hospitalization, and 6 (1.5%) were considered life-threatening.
Is Constipation Listed in the Official Label?
Yes, Constipation is listed as a known adverse reaction in the official FDA drug label for SELINEXOR.
What Other Side Effects Does SELINEXOR Cause?
Nausea (2,372)
Fatigue (1,795)
Decreased appetite (1,290)
Diarrhoea (1,190)
Plasma cell myeloma (1,046)
Vomiting (860)
Asthenia (794)
Death (761)
Thrombocytopenia (692)
Platelet count decreased (610)
What Other Drugs Cause Constipation?
LENALIDOMIDE (9,635)
NIRAPARIB (4,128)
ADALIMUMAB (4,063)
SEMAGLUTIDE (4,036)
TIRZEPATIDE (3,417)
ERENUMAB-AOOE (3,104)
MORPHINE (2,979)
OXYCODONE (2,747)
PALBOCICLIB (2,705)
POMALIDOMIDE (2,374)
Which SELINEXOR Alternatives Have Lower Constipation Risk?
SELINEXOR vs SELPERCATINIB
SELINEXOR vs SELUMETINIB
SELINEXOR vs SEMAGLUTIDE
SELINEXOR vs SEMUSTINE
SELINEXOR vs SENNA LEAF