SEMUSTINE for Bone marrow conditioning regimen: Side Effects & Safety Data
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There are 96 adverse event reports in the FDA FAERS database where SEMUSTINE was used for Bone marrow conditioning regimen.
Most Reported Side Effects for SEMUSTINE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Pneumonia | 25 | 16.0% | 7 | 4 |
| Febrile neutropenia | 21 | 13.5% | 0 | 6 |
| Product use in unapproved indication | 16 | 10.3% | 9 | 0 |
| Cystitis haemorrhagic | 14 | 9.0% | 3 | 2 |
| Drug ineffective | 14 | 9.0% | 4 | 2 |
| Off label use | 13 | 8.3% | 5 | 2 |
| Complications of bone marrow transplant | 12 | 7.7% | 9 | 0 |
| Infection | 12 | 7.7% | 12 | 0 |
| Post transplant lymphoproliferative disorder | 12 | 7.7% | 7 | 0 |
| Pulmonary alveolar haemorrhage | 12 | 7.7% | 9 | 0 |
| Gastrointestinal disorder | 11 | 7.1% | 0 | 0 |
| Epstein-barr viraemia | 10 | 6.4% | 6 | 0 |
| Haematotoxicity | 9 | 5.8% | 0 | 0 |
| Cytomegalovirus infection | 8 | 5.1% | 3 | 2 |
| Thrombocytopenia | 8 | 5.1% | 2 | 4 |
Other Indications for SEMUSTINE
Stem cell transplant (44)
Allogenic stem cell transplantation (15)
Acute myeloid leukaemia (11)
Prophylaxis against transplant rejection (10)
Acute lymphocytic leukaemia (8)
Prophylaxis against graft versus host disease (6)
Other Drugs Used for Bone marrow conditioning regimen
FLUDARABINE (6,080)
BUSULFAN (4,669)
CYCLOPHOSPHAMIDE (4,485)
MELPHALAN (2,368)
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN (1,884)
THIOTEPA (1,551)
ALEMTUZUMAB (1,122)
ETOPOSIDE (936)
CYTARABINE (833)
THYMOCYTE IMMUNE GLOBULIN NOS (742)