SILTUXIMAB for Castleman's disease: Side Effects & Safety Data

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There are 222 adverse event reports in the FDA FAERS database where SILTUXIMAB was used for Castleman's disease.

Most Reported Side Effects for SILTUXIMAB

Side Effect	Reports	%	Deaths	Hosp.
Off label use	96	20.3%	27	27
Drug ineffective	72	15.3%	16	42
Disease progression	32	6.8%	17	5
Immune effector cell-associated neurotoxicity syndrome	28	5.9%	16	4
Death	27	5.7%	27	1
Cytokine release syndrome	26	5.5%	18	9
Hypertension	24	5.1%	2	18
Product use in unapproved indication	24	5.1%	9	5
Drug effective for unapproved indication	23	4.9%	0	0
Cataract	19	4.0%	0	17
Condition aggravated	19	4.0%	16	4
Cushingoid	17	3.6%	0	15
Fracture	17	3.6%	0	15
Hepatic steatosis	17	3.6%	0	15
Osteopenia	17	3.6%	0	15