Does SIMVASTATIN Cause Cholestasis? 138 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 138 reports of Cholestasis have been filed in association with SIMVASTATIN (Simvastatin). This represents 0.5% of all adverse event reports for SIMVASTATIN.
138
Reports of Cholestasis with SIMVASTATIN
0.5%
of all SIMVASTATIN reports
7
Deaths
91
Hospitalizations
How Dangerous Is Cholestasis From SIMVASTATIN?
Of the 138 reports, 7 (5.1%) resulted in death, 91 (65.9%) required hospitalization, and 9 (6.5%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SIMVASTATIN. However, 138 reports have been filed with the FAERS database.
What Other Side Effects Does SIMVASTATIN Cause?
Myalgia (3,919)
Fatigue (2,066)
Arthralgia (1,775)
Drug interaction (1,744)
Nausea (1,676)
Rhabdomyolysis (1,616)
Dyspnoea (1,542)
Headache (1,470)
Drug hypersensitivity (1,433)
Muscular weakness (1,356)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which SIMVASTATIN Alternatives Have Lower Cholestasis Risk?
SIMVASTATIN vs SINGULAIR
SIMVASTATIN vs SINTILIMAB
SIMVASTATIN vs SIPONIMOD
SIMVASTATIN vs SIPULEUCEL-T
SIMVASTATIN vs SIROLIMUS