Does SIROLIMUS Cause Acute graft versus host disease? 157 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 157 reports of Acute graft versus host disease have been filed in association with SIROLIMUS (sirolimus). This represents 1.4% of all adverse event reports for SIROLIMUS.
157
Reports of Acute graft versus host disease with SIROLIMUS
1.4%
of all SIROLIMUS reports
40
Deaths
32
Hospitalizations
How Dangerous Is Acute graft versus host disease From SIROLIMUS?
Of the 157 reports, 40 (25.5%) resulted in death, 32 (20.4%) required hospitalization, and 8 (5.1%) were considered life-threatening.
Is Acute graft versus host disease Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SIROLIMUS. However, 157 reports have been filed with the FAERS database.
What Other Side Effects Does SIROLIMUS Cause?
Off label use (1,960)
Drug ineffective (1,005)
Product use in unapproved indication (984)
Transplant rejection (698)
Pneumonia (599)
Product use issue (506)
Alopecia (491)
Acne (482)
Transplant dysfunction (468)
Condition aggravated (433)
What Other Drugs Cause Acute graft versus host disease?
CYCLOSPORINE (1,043)
MYCOPHENOLATE MOFETIL (1,021)
FLUDARABINE (715)
CYCLOPHOSPHAMIDE (710)
TACROLIMUS (686)
METHOTREXATE (656)
BUSULFAN (337)
THIOTEPA (331)
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN (245)
RUXOLITINIB (240)
Which SIROLIMUS Alternatives Have Lower Acute graft versus host disease Risk?
SIROLIMUS vs SIRUKUMAB
SIROLIMUS vs SITAGLIPTIN
SIROLIMUS vs SOAP
SIROLIMUS vs SODIUM
SIROLIMUS vs SODIUM BICARBONATE