Does METHOTREXATE Cause Acute graft versus host disease? 656 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 656 reports of Acute graft versus host disease have been filed in association with METHOTREXATE (Methotrexate). This represents 0.3% of all adverse event reports for METHOTREXATE.
656
Reports of Acute graft versus host disease with METHOTREXATE
0.3%
of all METHOTREXATE reports
183
Deaths
93
Hospitalizations
How Dangerous Is Acute graft versus host disease From METHOTREXATE?
Of the 656 reports, 183 (27.9%) resulted in death, 93 (14.2%) required hospitalization, and 28 (4.3%) were considered life-threatening.
Is Acute graft versus host disease Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 656 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Acute graft versus host disease?
CYCLOSPORINE (1,043)
MYCOPHENOLATE MOFETIL (1,021)
FLUDARABINE (715)
CYCLOPHOSPHAMIDE (710)
TACROLIMUS (686)
BUSULFAN (337)
THIOTEPA (331)
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN (245)
RUXOLITINIB (240)
MELPHALAN (224)
Which METHOTREXATE Alternatives Have Lower Acute graft versus host disease Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA