Does SIROLIMUS Cause Clostridium difficile colitis? 26 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 26 reports of Clostridium difficile colitis have been filed in association with SIROLIMUS (sirolimus). This represents 0.2% of all adverse event reports for SIROLIMUS.
26
Reports of Clostridium difficile colitis with SIROLIMUS
0.2%
of all SIROLIMUS reports
0
Deaths
12
Hospitalizations
How Dangerous Is Clostridium difficile colitis From SIROLIMUS?
Of the 26 reports, 12 (46.2%) required hospitalization, and 6 (23.1%) were considered life-threatening.
Is Clostridium difficile colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SIROLIMUS. However, 26 reports have been filed with the FAERS database.
What Other Side Effects Does SIROLIMUS Cause?
Off label use (1,960)
Drug ineffective (1,005)
Product use in unapproved indication (984)
Transplant rejection (698)
Pneumonia (599)
Product use issue (506)
Alopecia (491)
Acne (482)
Transplant dysfunction (468)
Condition aggravated (433)
What Other Drugs Cause Clostridium difficile colitis?
CYCLOPHOSPHAMIDE (717)
PREDNISONE (619)
DEXAMETHASONE (575)
METHOTREXATE (562)
ETOPOSIDE (503)
CYTARABINE (489)
VINCRISTINE (482)
LENALIDOMIDE (388)
METHYLPREDNISOLONE (385)
CIPROFLOXACIN (378)
Which SIROLIMUS Alternatives Have Lower Clostridium difficile colitis Risk?
SIROLIMUS vs SIRUKUMAB
SIROLIMUS vs SITAGLIPTIN
SIROLIMUS vs SOAP
SIROLIMUS vs SODIUM
SIROLIMUS vs SODIUM BICARBONATE