Does SIROLIMUS Cause Fibrosis? 8 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 8 reports of Fibrosis have been filed in association with SIROLIMUS (sirolimus). This represents 0.1% of all adverse event reports for SIROLIMUS.
8
Reports of Fibrosis with SIROLIMUS
0.1%
of all SIROLIMUS reports
1
Deaths
2
Hospitalizations
How Dangerous Is Fibrosis From SIROLIMUS?
Of the 8 reports, 1 (12.5%) resulted in death, 2 (25.0%) required hospitalization, and 1 (12.5%) were considered life-threatening.
Is Fibrosis Listed in the Official Label?
Yes, Fibrosis is listed as a known adverse reaction in the official FDA drug label for SIROLIMUS.
What Other Side Effects Does SIROLIMUS Cause?
Off label use (1,960)
Drug ineffective (1,005)
Product use in unapproved indication (984)
Transplant rejection (698)
Pneumonia (599)
Product use issue (506)
Alopecia (491)
Acne (482)
Transplant dysfunction (468)
Condition aggravated (433)
What Other Drugs Cause Fibrosis?
METHOTREXATE (122)
ADALIMUMAB (118)
PREDNISONE (85)
RITUXIMAB (84)
MYCOPHENOLATE MOFETIL (70)
DICLOFENAC (67)
METFORMIN (52)
HYDROXYCHLOROQUINE (51)
TACROLIMUS (51)
ETANERCEPT (50)
Which SIROLIMUS Alternatives Have Lower Fibrosis Risk?
SIROLIMUS vs SIRUKUMAB
SIROLIMUS vs SITAGLIPTIN
SIROLIMUS vs SOAP
SIROLIMUS vs SODIUM
SIROLIMUS vs SODIUM BICARBONATE