Does SIROLIMUS Cause Progressive multifocal leukoencephalopathy? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Progressive multifocal leukoencephalopathy have been filed in association with SIROLIMUS (sirolimus). This represents 0.2% of all adverse event reports for SIROLIMUS.
27
Reports of Progressive multifocal leukoencephalopathy with SIROLIMUS
0.2%
of all SIROLIMUS reports
15
Deaths
12
Hospitalizations
How Dangerous Is Progressive multifocal leukoencephalopathy From SIROLIMUS?
Of the 27 reports, 15 (55.6%) resulted in death, 12 (44.4%) required hospitalization, and 2 (7.4%) were considered life-threatening.
Is Progressive multifocal leukoencephalopathy Listed in the Official Label?
Yes, Progressive multifocal leukoencephalopathy is listed as a known adverse reaction in the official FDA drug label for SIROLIMUS.
What Other Side Effects Does SIROLIMUS Cause?
Off label use (1,960)
Drug ineffective (1,005)
Product use in unapproved indication (984)
Transplant rejection (698)
Pneumonia (599)
Product use issue (506)
Alopecia (491)
Acne (482)
Transplant dysfunction (468)
Condition aggravated (433)
What Other Drugs Cause Progressive multifocal leukoencephalopathy?
NATALIZUMAB (1,668)
RITUXIMAB (1,647)
CYCLOPHOSPHAMIDE (782)
PREDNISONE (606)
PREDNISOLONE (439)
TACROLIMUS (438)
METHOTREXATE (428)
DOXORUBICIN (421)
MYCOPHENOLATE MOFETIL (414)
VINCRISTINE (376)
Which SIROLIMUS Alternatives Have Lower Progressive multifocal leukoencephalopathy Risk?
SIROLIMUS vs SIRUKUMAB
SIROLIMUS vs SITAGLIPTIN
SIROLIMUS vs SOAP
SIROLIMUS vs SODIUM
SIROLIMUS vs SODIUM BICARBONATE