Does SIROLIMUS Cause Renal impairment? 236 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 236 reports of Renal impairment have been filed in association with SIROLIMUS (sirolimus). This represents 2.1% of all adverse event reports for SIROLIMUS.
236
Reports of Renal impairment with SIROLIMUS
2.1%
of all SIROLIMUS reports
38
Deaths
117
Hospitalizations
How Dangerous Is Renal impairment From SIROLIMUS?
Of the 236 reports, 38 (16.1%) resulted in death, 117 (49.6%) required hospitalization, and 26 (11.0%) were considered life-threatening.
Is Renal impairment Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SIROLIMUS. However, 236 reports have been filed with the FAERS database.
What Other Side Effects Does SIROLIMUS Cause?
Off label use (1,960)
Drug ineffective (1,005)
Product use in unapproved indication (984)
Transplant rejection (698)
Pneumonia (599)
Product use issue (506)
Alopecia (491)
Acne (482)
Transplant dysfunction (468)
Condition aggravated (433)
What Other Drugs Cause Renal impairment?
LENALIDOMIDE (2,161)
EMTRICITABINE\TENOFOVIR DISOPROXIL (2,128)
TACROLIMUS (2,124)
OMEPRAZOLE (2,075)
LANSOPRAZOLE (2,063)
METHOTREXATE (1,852)
ESOMEPRAZOLE (1,811)
PANTOPRAZOLE (1,713)
SACUBITRIL\VALSARTAN (1,610)
CYCLOSPORINE (1,489)
Which SIROLIMUS Alternatives Have Lower Renal impairment Risk?
SIROLIMUS vs SIRUKUMAB
SIROLIMUS vs SITAGLIPTIN
SIROLIMUS vs SOAP
SIROLIMUS vs SODIUM
SIROLIMUS vs SODIUM BICARBONATE