Does SIROLIMUS Cause Thrombotic microangiopathy? 278 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 278 reports of Thrombotic microangiopathy have been filed in association with SIROLIMUS (sirolimus). This represents 2.4% of all adverse event reports for SIROLIMUS.
278
Reports of Thrombotic microangiopathy with SIROLIMUS
2.4%
of all SIROLIMUS reports
57
Deaths
108
Hospitalizations
How Dangerous Is Thrombotic microangiopathy From SIROLIMUS?
Of the 278 reports, 57 (20.5%) resulted in death, 108 (38.8%) required hospitalization, and 15 (5.4%) were considered life-threatening.
Is Thrombotic microangiopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SIROLIMUS. However, 278 reports have been filed with the FAERS database.
What Other Side Effects Does SIROLIMUS Cause?
Off label use (1,960)
Drug ineffective (1,005)
Product use in unapproved indication (984)
Transplant rejection (698)
Pneumonia (599)
Product use issue (506)
Alopecia (491)
Acne (482)
Transplant dysfunction (468)
Condition aggravated (433)
What Other Drugs Cause Thrombotic microangiopathy?
TACROLIMUS (1,982)
MYCOPHENOLATE MOFETIL (820)
CYCLOSPORINE (724)
GEMCITABINE (648)
ECULIZUMAB (636)
CYCLOPHOSPHAMIDE (602)
FLUDARABINE (480)
METHOTREXATE (447)
CARFILZOMIB (350)
METHYLPREDNISOLONE (345)
Which SIROLIMUS Alternatives Have Lower Thrombotic microangiopathy Risk?
SIROLIMUS vs SIRUKUMAB
SIROLIMUS vs SITAGLIPTIN
SIROLIMUS vs SOAP
SIROLIMUS vs SODIUM
SIROLIMUS vs SODIUM BICARBONATE