Does SITAGLIPTIN Cause Cholestasis? 56 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 56 reports of Cholestasis have been filed in association with SITAGLIPTIN (JANUVIA). This represents 0.3% of all adverse event reports for SITAGLIPTIN.
56
Reports of Cholestasis with SITAGLIPTIN
0.3%
of all SITAGLIPTIN reports
9
Deaths
54
Hospitalizations
How Dangerous Is Cholestasis From SITAGLIPTIN?
Of the 56 reports, 9 (16.1%) resulted in death, 54 (96.4%) required hospitalization, and 3 (5.4%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SITAGLIPTIN. However, 56 reports have been filed with the FAERS database.
What Other Side Effects Does SITAGLIPTIN Cause?
Blood glucose increased (1,427)
Pancreatic carcinoma (1,142)
Product dose omission issue (1,125)
Drug ineffective (1,057)
No adverse event (994)
Nausea (936)
Pancreatitis (922)
Diabetes mellitus inadequate control (744)
Diarrhoea (712)
Hypoglycaemia (674)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which SITAGLIPTIN Alternatives Have Lower Cholestasis Risk?
SITAGLIPTIN vs SOAP
SITAGLIPTIN vs SODIUM
SITAGLIPTIN vs SODIUM BICARBONATE
SITAGLIPTIN vs SODIUM BICARBONATE\SODIUM
SITAGLIPTIN vs SODIUM BORATE