Does SOFOSBUVIR Cause Pruritus? 647 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 647 reports of Pruritus have been filed in association with SOFOSBUVIR (Epclusa). This represents 3.7% of all adverse event reports for SOFOSBUVIR.
647
Reports of Pruritus with SOFOSBUVIR
3.7%
of all SOFOSBUVIR reports
226
Deaths
70
Hospitalizations
How Dangerous Is Pruritus From SOFOSBUVIR?
Of the 647 reports, 226 (34.9%) resulted in death, 70 (10.8%) required hospitalization, and 11 (1.7%) were considered life-threatening.
Is Pruritus Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SOFOSBUVIR. However, 647 reports have been filed with the FAERS database.
What Other Side Effects Does SOFOSBUVIR Cause?
Fatigue (2,004)
Drug ineffective (1,833)
Hepatitis c (1,662)
Headache (1,417)
Nausea (1,211)
Off label use (1,184)
Anaemia (1,065)
Insomnia (940)
Hepatocellular carcinoma (877)
Treatment failure (806)
What Other Drugs Cause Pruritus?
DUPILUMAB (44,279)
ADAPALENE (12,072)
ADALIMUMAB (9,644)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (9,439)
SECUKINUMAB (8,755)
ETANERCEPT (8,047)
METHOTREXATE (7,526)
LENALIDOMIDE (6,304)
TOCILIZUMAB (5,973)
RITUXIMAB (5,548)
Which SOFOSBUVIR Alternatives Have Lower Pruritus Risk?
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR\VOXILAPREVIR
SOFOSBUVIR vs SOLIFENACIN
SOFOSBUVIR vs SOLIRIS
SOFOSBUVIR vs SOLOSTAR