Does SOFOSBUVIR Cause Renal impairment? 214 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 214 reports of Renal impairment have been filed in association with SOFOSBUVIR (Epclusa). This represents 1.2% of all adverse event reports for SOFOSBUVIR.
214
Reports of Renal impairment with SOFOSBUVIR
1.2%
of all SOFOSBUVIR reports
61
Deaths
105
Hospitalizations
How Dangerous Is Renal impairment From SOFOSBUVIR?
Of the 214 reports, 61 (28.5%) resulted in death, 105 (49.1%) required hospitalization, and 8 (3.7%) were considered life-threatening.
Is Renal impairment Listed in the Official Label?
Yes, Renal impairment is listed as a known adverse reaction in the official FDA drug label for SOFOSBUVIR.
What Other Side Effects Does SOFOSBUVIR Cause?
Fatigue (2,004)
Drug ineffective (1,833)
Hepatitis c (1,662)
Headache (1,417)
Nausea (1,211)
Off label use (1,184)
Anaemia (1,065)
Insomnia (940)
Hepatocellular carcinoma (877)
Treatment failure (806)
What Other Drugs Cause Renal impairment?
LENALIDOMIDE (2,161)
EMTRICITABINE\TENOFOVIR DISOPROXIL (2,128)
TACROLIMUS (2,124)
OMEPRAZOLE (2,075)
LANSOPRAZOLE (2,063)
METHOTREXATE (1,852)
ESOMEPRAZOLE (1,811)
PANTOPRAZOLE (1,713)
SACUBITRIL\VALSARTAN (1,610)
CYCLOSPORINE (1,489)
Which SOFOSBUVIR Alternatives Have Lower Renal impairment Risk?
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR\VOXILAPREVIR
SOFOSBUVIR vs SOLIFENACIN
SOFOSBUVIR vs SOLIRIS
SOFOSBUVIR vs SOLOSTAR