Does SOFOSBUVIR Cause Sinus node dysfunction? 26 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 26 reports of Sinus node dysfunction have been filed in association with SOFOSBUVIR (Epclusa). This represents 0.2% of all adverse event reports for SOFOSBUVIR.
26
Reports of Sinus node dysfunction with SOFOSBUVIR
0.2%
of all SOFOSBUVIR reports
2
Deaths
16
Hospitalizations
How Dangerous Is Sinus node dysfunction From SOFOSBUVIR?
Of the 26 reports, 2 (7.7%) resulted in death, 16 (61.5%) required hospitalization, and 3 (11.5%) were considered life-threatening.
Is Sinus node dysfunction Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SOFOSBUVIR. However, 26 reports have been filed with the FAERS database.
What Other Side Effects Does SOFOSBUVIR Cause?
Fatigue (2,004)
Drug ineffective (1,833)
Hepatitis c (1,662)
Headache (1,417)
Nausea (1,211)
Off label use (1,184)
Anaemia (1,065)
Insomnia (940)
Hepatocellular carcinoma (877)
Treatment failure (806)
What Other Drugs Cause Sinus node dysfunction?
AMIODARONE (119)
METOPROLOL (101)
BISOPROLOL (84)
DEXAMETHASONE (69)
APIXABAN (67)
LENALIDOMIDE (66)
LACOSAMIDE (50)
DONEPEZIL (49)
METHOTREXATE (49)
ROSIGLITAZONE (48)
Which SOFOSBUVIR Alternatives Have Lower Sinus node dysfunction Risk?
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR\VOXILAPREVIR
SOFOSBUVIR vs SOLIFENACIN
SOFOSBUVIR vs SOLIRIS
SOFOSBUVIR vs SOLOSTAR