Does METHOTREXATE Cause Sinus node dysfunction? 49 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 49 reports of Sinus node dysfunction have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
49
Reports of Sinus node dysfunction with METHOTREXATE
0.0%
of all METHOTREXATE reports
5
Deaths
38
Hospitalizations
How Dangerous Is Sinus node dysfunction From METHOTREXATE?
Of the 49 reports, 5 (10.2%) resulted in death, 38 (77.6%) required hospitalization, and 2 (4.1%) were considered life-threatening.
Is Sinus node dysfunction Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 49 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Sinus node dysfunction?
AMIODARONE (119)
METOPROLOL (101)
BISOPROLOL (84)
DEXAMETHASONE (69)
APIXABAN (67)
LENALIDOMIDE (66)
LACOSAMIDE (50)
DONEPEZIL (49)
ROSIGLITAZONE (48)
FUROSEMIDE (41)
Which METHOTREXATE Alternatives Have Lower Sinus node dysfunction Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA