Sinus node dysfunction: Which Medications Cause It? (1,697 Reports Across 166 Drugs)
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Sinus node dysfunction has been reported as an adverse event with 166 different drugs in the FDA's FAERS database, with 1,697 total reports. 135 of these reports resulted in death.The drugs most commonly associated with Sinus node dysfunction are AMIODARONE, METOPROLOL, and BISOPROLOL.
1,697
Total Reports
166
Drugs Involved
135
Deaths
1,127
Hospitalizations
69.3 yrs
Average Patient Age
53.6% / 46.4%
Female / Male
Which Drugs Cause Sinus node dysfunction Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| AMIODARONE | 119 | 0.5% | 10 | 84 | 31 |
| METOPROLOL | 101 | 0.2% | 1 | 67 | 7 |
| BISOPROLOL | 84 | 0.3% | 1 | 61 | 15 |
| DEXAMETHASONE | 69 | 0.1% | 6 | 53 | 11 |
| APIXABAN | 67 | 0.0% | 3 | 25 | 8 |
| LENALIDOMIDE | 66 | 0.0% | 9 | 48 | 3 |
| LACOSAMIDE | 50 | 0.2% | 2 | 29 | 11 |
| DONEPEZIL | 49 | 0.6% | 0 | 42 | 3 |
| METHOTREXATE | 49 | 0.0% | 5 | 38 | 2 |
| ROSIGLITAZONE | 48 | 0.1% | 4 | 46 | 0 |
| FUROSEMIDE | 41 | 0.1% | 1 | 25 | 8 |
| LITHIUM | 40 | 0.3% | 0 | 29 | 11 |
| AMLODIPINE | 39 | 0.1% | 0 | 27 | 1 |
| ADALIMUMAB | 38 | 0.0% | 0 | 26 | 0 |
| DIGOXIN | 38 | 0.5% | 2 | 33 | 8 |
| IBRUTINIB | 36 | 0.1% | 8 | 27 | 7 |
| LEVETIRACETAM | 36 | 0.1% | 3 | 30 | 11 |
| ATENOLOL | 33 | 0.3% | 1 | 20 | 11 |
| CARVEDILOL | 31 | 0.2% | 4 | 29 | 17 |
| TICAGRELOR | 29 | 0.1% | 2 | 17 | 7 |