SORAFENIB for Constipation: Side Effects & Safety Data
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There are 5 adverse event reports in the FDA FAERS database where SORAFENIB was used for Constipation.
Most Reported Side Effects for SORAFENIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Hepatocellular carcinoma | 1,665 | 15.3% | 492 | 306 |
| Diarrhoea | 1,611 | 14.8% | 301 | 619 |
| Off label use | 1,587 | 14.6% | 301 | 563 |
| Fatigue | 1,041 | 9.5% | 179 | 450 |
| Palmar-plantar erythrodysaesthesia syndrome | 1,040 | 9.5% | 202 | 233 |
| Decreased appetite | 906 | 8.3% | 241 | 420 |
| Death | 904 | 8.3% | 901 | 236 |
| Asthenia | 777 | 7.1% | 231 | 415 |
| Nausea | 716 | 6.6% | 139 | 350 |
| Rash | 613 | 5.6% | 103 | 214 |
| Weight decreased | 598 | 5.5% | 144 | 274 |
| Vomiting | 544 | 5.0% | 126 | 308 |
| Hypertension | 517 | 4.7% | 95 | 178 |
| Pain in extremity | 497 | 4.6% | 65 | 182 |
| Pyrexia | 493 | 4.5% | 118 | 288 |
Other Indications for SORAFENIB
Hepatocellular carcinoma (4,986)
Hepatic cancer (1,167)
Acute myeloid leukaemia (620)
Renal cell carcinoma (454)
Thyroid cancer (399)
Product used for unknown indication (234)
Metastases to lung (182)
Renal cancer (179)
Metastatic renal cell carcinoma (134)
Neoplasm malignant (121)
Other Drugs Used for Constipation
POLYETHYLENE GLYCOL 3350 (9,960)
LINACLOTIDE (5,348)
NALOXEGOL OXALATE (1,418)
LACTULOSE (1,115)
BISACODYL (1,013)
POLYETHYLENE GLYCOL 3350\POTASSIUM\SODIUM BICARBONATE\SODIUM (709)
POLYETHYLENE GLYCOLS (667)
MAGNESIUM (648)
MAGNESIUM HYDROXIDE (635)
LUBIPROSTONE (563)