Does SOTORASIB Cause Cardiac failure? 11 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 11 reports of Cardiac failure have been filed in association with SOTORASIB (LUMAKRAS). This represents 0.4% of all adverse event reports for SOTORASIB.
11
Reports of Cardiac failure with SOTORASIB
0.4%
of all SOTORASIB reports
5
Deaths
4
Hospitalizations
How Dangerous Is Cardiac failure From SOTORASIB?
Of the 11 reports, 5 (45.5%) resulted in death, 4 (36.4%) required hospitalization, and 1 (9.1%) were considered life-threatening.
Is Cardiac failure Listed in the Official Label?
Yes, Cardiac failure is listed as a known adverse reaction in the official FDA drug label for SOTORASIB.
What Other Side Effects Does SOTORASIB Cause?
Non-small cell lung cancer (483)
Death (319)
Disease progression (314)
Diarrhoea (284)
Off label use (193)
Nausea (98)
Non-small cell lung cancer metastatic (93)
Hepatotoxicity (91)
Fatigue (87)
Hepatic function abnormal (80)
What Other Drugs Cause Cardiac failure?
SACUBITRIL\VALSARTAN (4,504)
FUROSEMIDE (1,841)
APIXABAN (1,575)
CYCLOPHOSPHAMIDE (1,514)
DOXORUBICIN (1,367)
ADALIMUMAB (1,278)
DEXAMETHASONE (1,271)
TREPROSTINIL (1,168)
BISOPROLOL (1,159)
LENALIDOMIDE (1,115)
Which SOTORASIB Alternatives Have Lower Cardiac failure Risk?
SOTORASIB vs SOTROVIMAB
SOTORASIB vs SOVALDI
SOTORASIB vs SOYBEAN OIL
SOTORASIB vs SPARSENTAN
SOTORASIB vs SPARTALIZUMAB