Does SOTORASIB Cause Hypocalcaemia? 14 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 14 reports of Hypocalcaemia have been filed in association with SOTORASIB (LUMAKRAS). This represents 0.5% of all adverse event reports for SOTORASIB.
14
Reports of Hypocalcaemia with SOTORASIB
0.5%
of all SOTORASIB reports
3
Deaths
12
Hospitalizations
How Dangerous Is Hypocalcaemia From SOTORASIB?
Of the 14 reports, 3 (21.4%) resulted in death, 12 (85.7%) required hospitalization, and 6 (42.9%) were considered life-threatening.
Is Hypocalcaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SOTORASIB. However, 14 reports have been filed with the FAERS database.
What Other Side Effects Does SOTORASIB Cause?
Non-small cell lung cancer (483)
Death (319)
Disease progression (314)
Diarrhoea (284)
Off label use (193)
Nausea (98)
Non-small cell lung cancer metastatic (93)
Hepatotoxicity (91)
Fatigue (87)
Hepatic function abnormal (80)
What Other Drugs Cause Hypocalcaemia?
DENOSUMAB (2,345)
OMEPRAZOLE (966)
PANTOPRAZOLE (935)
PARATHYROID HORMONE (784)
ZOLEDRONIC ACID (513)
CINACALCET (468)
ESOMEPRAZOLE (451)
FUROSEMIDE (429)
DEXAMETHASONE (368)
PREDNISONE (352)
Which SOTORASIB Alternatives Have Lower Hypocalcaemia Risk?
SOTORASIB vs SOTROVIMAB
SOTORASIB vs SOVALDI
SOTORASIB vs SOYBEAN OIL
SOTORASIB vs SPARSENTAN
SOTORASIB vs SPARTALIZUMAB