Does SPIRONOLACTONE Cause Adrenal insufficiency? 11 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 11 reports of Adrenal insufficiency have been filed in association with SPIRONOLACTONE (spironolactone). This represents 0.1% of all adverse event reports for SPIRONOLACTONE.
11
Reports of Adrenal insufficiency with SPIRONOLACTONE
0.1%
of all SPIRONOLACTONE reports
2
Deaths
8
Hospitalizations
How Dangerous Is Adrenal insufficiency From SPIRONOLACTONE?
Of the 11 reports, 2 (18.2%) resulted in death, 8 (72.7%) required hospitalization, and 1 (9.1%) were considered life-threatening.
Is Adrenal insufficiency Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SPIRONOLACTONE. However, 11 reports have been filed with the FAERS database.
What Other Side Effects Does SPIRONOLACTONE Cause?
Acute kidney injury (3,273)
Hyperkalaemia (2,518)
Hypotension (1,583)
Dyspnoea (1,468)
Drug ineffective (1,379)
Hyponatraemia (1,166)
Dizziness (991)
Fatigue (990)
Fall (947)
Off label use (899)
What Other Drugs Cause Adrenal insufficiency?
NIVOLUMAB (1,285)
PEMBROLIZUMAB (1,270)
PREDNISONE (1,105)
IPILIMUMAB (851)
METHOTREXATE (644)
ADALIMUMAB (554)
ETANERCEPT (546)
TOCILIZUMAB (541)
HYDROXYCHLOROQUINE (517)
INFLIXIMAB (509)
Which SPIRONOLACTONE Alternatives Have Lower Adrenal insufficiency Risk?
SPIRONOLACTONE vs SPRYCEL
SPIRONOLACTONE vs STALEVO
SPIRONOLACTONE vs STANNOUS FLUORIDE
SPIRONOLACTONE vs STANOZOLOL
SPIRONOLACTONE vs STAVUDINE