Does SPIRONOLACTONE Cause Cholestasis? 61 Reports in FDA Database
Lower Your Cholesterol — The Natural Way
The Oxidized Cholesterol Strategy: a science-backed plan for heart health.
According to the FDA Adverse Event Reporting System (FAERS), 61 reports of Cholestasis have been filed in association with SPIRONOLACTONE (spironolactone). This represents 0.3% of all adverse event reports for SPIRONOLACTONE.
61
Reports of Cholestasis with SPIRONOLACTONE
0.3%
of all SPIRONOLACTONE reports
19
Deaths
27
Hospitalizations
How Dangerous Is Cholestasis From SPIRONOLACTONE?
Of the 61 reports, 19 (31.1%) resulted in death, 27 (44.3%) required hospitalization, and 5 (8.2%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SPIRONOLACTONE. However, 61 reports have been filed with the FAERS database.
What Other Side Effects Does SPIRONOLACTONE Cause?
Acute kidney injury (3,273)
Hyperkalaemia (2,518)
Hypotension (1,583)
Dyspnoea (1,468)
Drug ineffective (1,379)
Hyponatraemia (1,166)
Dizziness (991)
Fatigue (990)
Fall (947)
Off label use (899)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which SPIRONOLACTONE Alternatives Have Lower Cholestasis Risk?
SPIRONOLACTONE vs SPRYCEL
SPIRONOLACTONE vs STALEVO
SPIRONOLACTONE vs STANNOUS FLUORIDE
SPIRONOLACTONE vs STANOZOLOL
SPIRONOLACTONE vs STAVUDINE