Does SPIRONOLACTONE Cause Extremity necrosis? 9 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 9 reports of Extremity necrosis have been filed in association with SPIRONOLACTONE (spironolactone). This represents 0.0% of all adverse event reports for SPIRONOLACTONE.
9
Reports of Extremity necrosis with SPIRONOLACTONE
0.0%
of all SPIRONOLACTONE reports
1
Deaths
8
Hospitalizations
How Dangerous Is Extremity necrosis From SPIRONOLACTONE?
Of the 9 reports, 1 (11.1%) resulted in death, 8 (88.9%) required hospitalization.
Is Extremity necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SPIRONOLACTONE. However, 9 reports have been filed with the FAERS database.
What Other Side Effects Does SPIRONOLACTONE Cause?
Acute kidney injury (3,273)
Hyperkalaemia (2,518)
Hypotension (1,583)
Dyspnoea (1,468)
Drug ineffective (1,379)
Hyponatraemia (1,166)
Dizziness (991)
Fatigue (990)
Fall (947)
Off label use (899)
What Other Drugs Cause Extremity necrosis?
CANAGLIFLOZIN (95)
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (84)
CARBOPLATIN (46)
PEMETREXED (45)
ADALIMUMAB (42)
GEMCITABINE (40)
METHYLPREDNISOLONE (40)
EPINEPHRINE (39)
PEMBROLIZUMAB (37)
NOREPINEPHRINE (34)
Which SPIRONOLACTONE Alternatives Have Lower Extremity necrosis Risk?
SPIRONOLACTONE vs SPRYCEL
SPIRONOLACTONE vs STALEVO
SPIRONOLACTONE vs STANNOUS FLUORIDE
SPIRONOLACTONE vs STANOZOLOL
SPIRONOLACTONE vs STAVUDINE