Does SPIRONOLACTONE Cause Hyperlactacidaemia? 17 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 17 reports of Hyperlactacidaemia have been filed in association with SPIRONOLACTONE (spironolactone). This represents 0.1% of all adverse event reports for SPIRONOLACTONE.
17
Reports of Hyperlactacidaemia with SPIRONOLACTONE
0.1%
of all SPIRONOLACTONE reports
6
Deaths
17
Hospitalizations
How Dangerous Is Hyperlactacidaemia From SPIRONOLACTONE?
Of the 17 reports, 6 (35.3%) resulted in death, 17 (100.0%) required hospitalization, and 8 (47.1%) were considered life-threatening.
Is Hyperlactacidaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SPIRONOLACTONE. However, 17 reports have been filed with the FAERS database.
What Other Side Effects Does SPIRONOLACTONE Cause?
Acute kidney injury (3,273)
Hyperkalaemia (2,518)
Hypotension (1,583)
Dyspnoea (1,468)
Drug ineffective (1,379)
Hyponatraemia (1,166)
Dizziness (991)
Fatigue (990)
Fall (947)
Off label use (899)
What Other Drugs Cause Hyperlactacidaemia?
METFORMIN (807)
AMLODIPINE (105)
LINEZOLID (105)
ACETAMINOPHEN (96)
QUETIAPINE (68)
IBUPROFEN (55)
METHYLPREDNISOLONE (54)
LANSOPRAZOLE (52)
NOREPINEPHRINE (52)
MIRTAZAPINE (46)
Which SPIRONOLACTONE Alternatives Have Lower Hyperlactacidaemia Risk?
SPIRONOLACTONE vs SPRYCEL
SPIRONOLACTONE vs STALEVO
SPIRONOLACTONE vs STANNOUS FLUORIDE
SPIRONOLACTONE vs STANOZOLOL
SPIRONOLACTONE vs STAVUDINE