Does SPIRONOLACTONE Cause Hypervolaemia? 36 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 36 reports of Hypervolaemia have been filed in association with SPIRONOLACTONE (spironolactone). This represents 0.2% of all adverse event reports for SPIRONOLACTONE.
36
Reports of Hypervolaemia with SPIRONOLACTONE
0.2%
of all SPIRONOLACTONE reports
3
Deaths
32
Hospitalizations
How Dangerous Is Hypervolaemia From SPIRONOLACTONE?
Of the 36 reports, 3 (8.3%) resulted in death, 32 (88.9%) required hospitalization, and 5 (13.9%) were considered life-threatening.
Is Hypervolaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SPIRONOLACTONE. However, 36 reports have been filed with the FAERS database.
What Other Side Effects Does SPIRONOLACTONE Cause?
Acute kidney injury (3,273)
Hyperkalaemia (2,518)
Hypotension (1,583)
Dyspnoea (1,468)
Drug ineffective (1,379)
Hyponatraemia (1,166)
Dizziness (991)
Fatigue (990)
Fall (947)
Off label use (899)
What Other Drugs Cause Hypervolaemia?
TREPROSTINIL (580)
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (428)
AMBRISENTAN (205)
MACITENTAN (202)
FUROSEMIDE (139)
AMLODIPINE (122)
CYCLOPHOSPHAMIDE (118)
SACUBITRIL\VALSARTAN (115)
TACROLIMUS (100)
PREDNISONE (98)
Which SPIRONOLACTONE Alternatives Have Lower Hypervolaemia Risk?
SPIRONOLACTONE vs SPRYCEL
SPIRONOLACTONE vs STALEVO
SPIRONOLACTONE vs STANNOUS FLUORIDE
SPIRONOLACTONE vs STANOZOLOL
SPIRONOLACTONE vs STAVUDINE