Does SPIRONOLACTONE Cause Renal impairment? 685 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 685 reports of Renal impairment have been filed in association with SPIRONOLACTONE (spironolactone). This represents 3.3% of all adverse event reports for SPIRONOLACTONE.
685
Reports of Renal impairment with SPIRONOLACTONE
3.3%
of all SPIRONOLACTONE reports
48
Deaths
441
Hospitalizations
How Dangerous Is Renal impairment From SPIRONOLACTONE?
Of the 685 reports, 48 (7.0%) resulted in death, 441 (64.4%) required hospitalization, and 41 (6.0%) were considered life-threatening.
Is Renal impairment Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SPIRONOLACTONE. However, 685 reports have been filed with the FAERS database.
What Other Side Effects Does SPIRONOLACTONE Cause?
Acute kidney injury (3,273)
Hyperkalaemia (2,518)
Hypotension (1,583)
Dyspnoea (1,468)
Drug ineffective (1,379)
Hyponatraemia (1,166)
Dizziness (991)
Fatigue (990)
Fall (947)
Off label use (899)
What Other Drugs Cause Renal impairment?
LENALIDOMIDE (2,161)
EMTRICITABINE\TENOFOVIR DISOPROXIL (2,128)
TACROLIMUS (2,124)
OMEPRAZOLE (2,075)
LANSOPRAZOLE (2,063)
METHOTREXATE (1,852)
ESOMEPRAZOLE (1,811)
PANTOPRAZOLE (1,713)
SACUBITRIL\VALSARTAN (1,610)
CYCLOSPORINE (1,489)
Which SPIRONOLACTONE Alternatives Have Lower Renal impairment Risk?
SPIRONOLACTONE vs SPRYCEL
SPIRONOLACTONE vs STALEVO
SPIRONOLACTONE vs STANNOUS FLUORIDE
SPIRONOLACTONE vs STANOZOLOL
SPIRONOLACTONE vs STAVUDINE