Does TALAZOPARIB Cause Bone marrow failure? 5 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5 reports of Bone marrow failure have been filed in association with TALAZOPARIB (Talzenna). This represents 0.3% of all adverse event reports for TALAZOPARIB.
5
Reports of Bone marrow failure with TALAZOPARIB
0.3%
of all TALAZOPARIB reports
2
Deaths
2
Hospitalizations
How Dangerous Is Bone marrow failure From TALAZOPARIB?
Of the 5 reports, 2 (40.0%) resulted in death, 2 (40.0%) required hospitalization, and 2 (40.0%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TALAZOPARIB. However, 5 reports have been filed with the FAERS database.
What Other Side Effects Does TALAZOPARIB Cause?
Anaemia (219)
Neoplasm progression (169)
Death (142)
Off label use (78)
Thrombocytopenia (78)
Fatigue (77)
Platelet count decreased (68)
Haemoglobin decreased (65)
Febrile neutropenia (60)
Pancytopenia (60)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which TALAZOPARIB Alternatives Have Lower Bone marrow failure Risk?
TALAZOPARIB vs TALC
TALAZOPARIB vs TALIGLUCERASE ALFA
TALAZOPARIB vs TALIMOGENE LAHERPAREPVEC
TALAZOPARIB vs TALQUETAMAB
TALAZOPARIB vs TALQUETAMAB-TGVS