Does TAPENTADOL Cause Serotonin syndrome? 169 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 169 reports of Serotonin syndrome have been filed in association with TAPENTADOL (Nucynta). This represents 0.6% of all adverse event reports for TAPENTADOL.
169
Reports of Serotonin syndrome with TAPENTADOL
0.6%
of all TAPENTADOL reports
4
Deaths
70
Hospitalizations
How Dangerous Is Serotonin syndrome From TAPENTADOL?
Of the 169 reports, 4 (2.4%) resulted in death, 70 (41.4%) required hospitalization, and 15 (8.9%) were considered life-threatening.
Is Serotonin syndrome Listed in the Official Label?
Yes, Serotonin syndrome is listed as a known adverse reaction in the official FDA drug label for TAPENTADOL.
What Other Side Effects Does TAPENTADOL Cause?
Death (11,560)
Toxicity to various agents (9,617)
Overdose (5,843)
Drug abuse (1,566)
Drug dependence (1,019)
Drug withdrawal syndrome neonatal (945)
Accidental overdose (693)
Drug ineffective (633)
Pain (436)
Nausea (434)
What Other Drugs Cause Serotonin syndrome?
VENLAFAXINE (1,632)
SERTRALINE (1,563)
FLUOXETINE (1,457)
DULOXETINE (1,352)
TRAMADOL (1,229)
BUPROPION (1,058)
ESCITALOPRAM OXALATE (1,051)
QUETIAPINE (947)
TRAZODONE (831)
FENTANYL (778)
Which TAPENTADOL Alternatives Have Lower Serotonin syndrome Risk?
TAPENTADOL vs TAPINAROF
TAPENTADOL vs TARCEVA
TAPENTADOL vs TARLATAMAB
TAPENTADOL vs TARLATAMAB-DLLE
TAPENTADOL vs TASIGNA