Does THIOGUANINE Cause Clostridium difficile colitis? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Clostridium difficile colitis have been filed in association with THIOGUANINE (TABLOID). This represents 0.4% of all adverse event reports for THIOGUANINE.
6
Reports of Clostridium difficile colitis with THIOGUANINE
0.4%
of all THIOGUANINE reports
2
Deaths
3
Hospitalizations
How Dangerous Is Clostridium difficile colitis From THIOGUANINE?
Of the 6 reports, 2 (33.3%) resulted in death, 3 (50.0%) required hospitalization, and 1 (16.7%) were considered life-threatening.
Is Clostridium difficile colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for THIOGUANINE. However, 6 reports have been filed with the FAERS database.
What Other Side Effects Does THIOGUANINE Cause?
Febrile neutropenia (470)
Haematotoxicity (174)
Off label use (94)
Pyrexia (80)
Sepsis (76)
Febrile bone marrow aplasia (73)
Neutropenia (69)
Thrombocytopenia (64)
Pancytopenia (61)
Death (49)
What Other Drugs Cause Clostridium difficile colitis?
CYCLOPHOSPHAMIDE (717)
PREDNISONE (619)
DEXAMETHASONE (575)
METHOTREXATE (562)
ETOPOSIDE (503)
CYTARABINE (489)
VINCRISTINE (482)
LENALIDOMIDE (388)
METHYLPREDNISOLONE (385)
CIPROFLOXACIN (378)
Which THIOGUANINE Alternatives Have Lower Clostridium difficile colitis Risk?
THIOGUANINE vs THIOGUANINE ANHYDROUS
THIOGUANINE vs THIOPENTAL
THIOGUANINE vs THIORIDAZINE
THIOGUANINE vs THIOTEPA
THIOGUANINE vs THIOTHIXENE