Does THIOTEPA Cause Clostridium difficile colitis? 70 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 70 reports of Clostridium difficile colitis have been filed in association with THIOTEPA (Thiotepa). This represents 1.0% of all adverse event reports for THIOTEPA.
70
Reports of Clostridium difficile colitis with THIOTEPA
1.0%
of all THIOTEPA reports
11
Deaths
31
Hospitalizations
How Dangerous Is Clostridium difficile colitis From THIOTEPA?
Of the 70 reports, 11 (15.7%) resulted in death, 31 (44.3%) required hospitalization, and 9 (12.9%) were considered life-threatening.
Is Clostridium difficile colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for THIOTEPA. However, 70 reports have been filed with the FAERS database.
What Other Side Effects Does THIOTEPA Cause?
Off label use (762)
Febrile neutropenia (645)
Mucosal inflammation (616)
Cytomegalovirus infection (446)
Product use in unapproved indication (425)
Pyrexia (359)
Drug ineffective (358)
Acute graft versus host disease in skin (355)
Acute graft versus host disease (331)
Cytomegalovirus infection reactivation (325)
What Other Drugs Cause Clostridium difficile colitis?
CYCLOPHOSPHAMIDE (717)
PREDNISONE (619)
DEXAMETHASONE (575)
METHOTREXATE (562)
ETOPOSIDE (503)
CYTARABINE (489)
VINCRISTINE (482)
LENALIDOMIDE (388)
METHYLPREDNISOLONE (385)
CIPROFLOXACIN (378)
Which THIOTEPA Alternatives Have Lower Clostridium difficile colitis Risk?
THIOTEPA vs THIOTHIXENE
THIOTEPA vs THROMBIN
THIOTEPA vs THROMBIN HUMAN
THIOTEPA vs THYMOCYTE IMMUNE GLOBULIN NOS
THIOTEPA vs THYMOGLOBULINE