Does THIOTEPA Cause Haematotoxicity? 192 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 192 reports of Haematotoxicity have been filed in association with THIOTEPA (Thiotepa). This represents 2.8% of all adverse event reports for THIOTEPA.
192
Reports of Haematotoxicity with THIOTEPA
2.8%
of all THIOTEPA reports
8
Deaths
11
Hospitalizations
How Dangerous Is Haematotoxicity From THIOTEPA?
Of the 192 reports, 8 (4.2%) resulted in death, 11 (5.7%) required hospitalization, and 89 (46.4%) were considered life-threatening.
Is Haematotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for THIOTEPA. However, 192 reports have been filed with the FAERS database.
What Other Side Effects Does THIOTEPA Cause?
Off label use (762)
Febrile neutropenia (645)
Mucosal inflammation (616)
Cytomegalovirus infection (446)
Product use in unapproved indication (425)
Pyrexia (359)
Drug ineffective (358)
Acute graft versus host disease in skin (355)
Acute graft versus host disease (331)
Cytomegalovirus infection reactivation (325)
What Other Drugs Cause Haematotoxicity?
CYCLOPHOSPHAMIDE (1,410)
DOXORUBICIN (1,180)
VINCRISTINE (1,038)
RITUXIMAB (812)
CARBOPLATIN (803)
METHOTREXATE (799)
PREDNISONE (730)
CYTARABINE (701)
ETOPOSIDE (677)
CISPLATIN (668)
Which THIOTEPA Alternatives Have Lower Haematotoxicity Risk?
THIOTEPA vs THIOTHIXENE
THIOTEPA vs THROMBIN
THIOTEPA vs THROMBIN HUMAN
THIOTEPA vs THYMOCYTE IMMUNE GLOBULIN NOS
THIOTEPA vs THYMOGLOBULINE