Does THIOTEPA Cause Thrombotic microangiopathy? 209 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 209 reports of Thrombotic microangiopathy have been filed in association with THIOTEPA (Thiotepa). This represents 3.1% of all adverse event reports for THIOTEPA.
209
Reports of Thrombotic microangiopathy with THIOTEPA
3.1%
of all THIOTEPA reports
45
Deaths
27
Hospitalizations
How Dangerous Is Thrombotic microangiopathy From THIOTEPA?
Of the 209 reports, 45 (21.5%) resulted in death, 27 (12.9%) required hospitalization, and 15 (7.2%) were considered life-threatening.
Is Thrombotic microangiopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for THIOTEPA. However, 209 reports have been filed with the FAERS database.
What Other Side Effects Does THIOTEPA Cause?
Off label use (762)
Febrile neutropenia (645)
Mucosal inflammation (616)
Cytomegalovirus infection (446)
Product use in unapproved indication (425)
Pyrexia (359)
Drug ineffective (358)
Acute graft versus host disease in skin (355)
Acute graft versus host disease (331)
Cytomegalovirus infection reactivation (325)
What Other Drugs Cause Thrombotic microangiopathy?
TACROLIMUS (1,982)
MYCOPHENOLATE MOFETIL (820)
CYCLOSPORINE (724)
GEMCITABINE (648)
ECULIZUMAB (636)
CYCLOPHOSPHAMIDE (602)
FLUDARABINE (480)
METHOTREXATE (447)
CARFILZOMIB (350)
METHYLPREDNISOLONE (345)
Which THIOTEPA Alternatives Have Lower Thrombotic microangiopathy Risk?
THIOTEPA vs THIOTHIXENE
THIOTEPA vs THROMBIN
THIOTEPA vs THROMBIN HUMAN
THIOTEPA vs THYMOCYTE IMMUNE GLOBULIN NOS
THIOTEPA vs THYMOGLOBULINE