TISAGENLECLEUCEL for Diffuse large b-cell lymphoma refractory: Side Effects & Safety Data
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There are 72 adverse event reports in the FDA FAERS database where TISAGENLECLEUCEL was used for Diffuse large b-cell lymphoma refractory.
Most Reported Side Effects for TISAGENLECLEUCEL
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Cytokine release syndrome | 1,660 | 39.3% | 505 | 696 |
| Pyrexia | 1,030 | 24.4% | 311 | 427 |
| Malignant neoplasm progression | 582 | 13.8% | 400 | 126 |
| Hypotension | 425 | 10.1% | 156 | 214 |
| Immune effector cell-associated neurotoxicity syndrome | 416 | 9.8% | 127 | 183 |
| Neurotoxicity | 411 | 9.7% | 146 | 155 |
| Platelet count decreased | 397 | 9.4% | 182 | 77 |
| White blood cell count decreased | 392 | 9.3% | 164 | 59 |
| Hypogammaglobulinaemia | 374 | 8.8% | 126 | 38 |
| Lymphocyte count decreased | 365 | 8.6% | 139 | 38 |
| Acute lymphocytic leukaemia recurrent | 361 | 8.5% | 100 | 71 |
| Neutrophil count decreased | 358 | 8.5% | 134 | 58 |
| Haemoglobin decreased | 356 | 8.4% | 175 | 47 |
| Diffuse large b-cell lymphoma | 300 | 7.1% | 229 | 69 |
| Death | 282 | 6.7% | 282 | 30 |
Other Indications for TISAGENLECLEUCEL
Diffuse large b-cell lymphoma (1,321)
Acute lymphocytic leukaemia (928)
Product used for unknown indication (494)
B-cell type acute leukaemia (354)
Acute lymphocytic leukaemia recurrent (225)
Diffuse large b-cell lymphoma recurrent (118)
B-cell lymphoma (87)
Non-hodgkin's lymphoma (86)
Follicular lymphoma (82)
Lymphoma (61)
Other Drugs Used for Diffuse large b-cell lymphoma refractory
RITUXIMAB (667)
EPCORITAMAB-BYSP (353)
AXICABTAGENE CILOLEUCEL (336)
BENDAMUSTINE (283)
CYCLOPHOSPHAMIDE (226)
POLATUZUMAB VEDOTIN (223)
ETOPOSIDE (165)
POLATUZUMAB VEDOTIN-PIIQ (158)
GEMCITABINE (147)
LENALIDOMIDE (143)