Does TISAGENLECLEUCEL Cause Pyrexia? 1,030 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,030 reports of Pyrexia have been filed in association with TISAGENLECLEUCEL (KYMRIAH). This represents 24.4% of all adverse event reports for TISAGENLECLEUCEL.
1,030
Reports of Pyrexia with TISAGENLECLEUCEL
24.4%
of all TISAGENLECLEUCEL reports
311
Deaths
427
Hospitalizations
How Dangerous Is Pyrexia From TISAGENLECLEUCEL?
Of the 1,030 reports, 311 (30.2%) resulted in death, 427 (41.5%) required hospitalization, and 188 (18.3%) were considered life-threatening.
Is Pyrexia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TISAGENLECLEUCEL. However, 1,030 reports have been filed with the FAERS database.
What Other Side Effects Does TISAGENLECLEUCEL Cause?
Cytokine release syndrome (1,660)
Malignant neoplasm progression (582)
Hypotension (425)
Immune effector cell-associated neurotoxicity syndrome (416)
Neurotoxicity (411)
Platelet count decreased (397)
White blood cell count decreased (392)
Hypogammaglobulinaemia (374)
Lymphocyte count decreased (365)
Acute lymphocytic leukaemia recurrent (361)
What Other Drugs Cause Pyrexia?
ADALIMUMAB (12,160)
METHOTREXATE (10,158)
RITUXIMAB (10,061)
PREDNISONE (8,141)
ETANERCEPT (7,626)
INFLIXIMAB (6,560)
ACETAMINOPHEN (6,414)
CYCLOPHOSPHAMIDE (6,126)
TOCILIZUMAB (5,529)
LENALIDOMIDE (5,496)
Which TISAGENLECLEUCEL Alternatives Have Lower Pyrexia Risk?
TISAGENLECLEUCEL vs TISLELIZUMAB
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN-TFTV
TISAGENLECLEUCEL vs TITANIUM DIOXIDE\ZINC
TISAGENLECLEUCEL vs TIVICAY