Does TISAGENLECLEUCEL Cause Hypotension? 425 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 425 reports of Hypotension have been filed in association with TISAGENLECLEUCEL (KYMRIAH). This represents 10.1% of all adverse event reports for TISAGENLECLEUCEL.
425
Reports of Hypotension with TISAGENLECLEUCEL
10.1%
of all TISAGENLECLEUCEL reports
156
Deaths
214
Hospitalizations
How Dangerous Is Hypotension From TISAGENLECLEUCEL?
Of the 425 reports, 156 (36.7%) resulted in death, 214 (50.4%) required hospitalization, and 116 (27.3%) were considered life-threatening.
Is Hypotension Listed in the Official Label?
Yes, Hypotension is listed as a known adverse reaction in the official FDA drug label for TISAGENLECLEUCEL.
What Other Side Effects Does TISAGENLECLEUCEL Cause?
Cytokine release syndrome (1,660)
Pyrexia (1,030)
Malignant neoplasm progression (582)
Immune effector cell-associated neurotoxicity syndrome (416)
Neurotoxicity (411)
Platelet count decreased (397)
White blood cell count decreased (392)
Hypogammaglobulinaemia (374)
Lymphocyte count decreased (365)
Acute lymphocytic leukaemia recurrent (361)
What Other Drugs Cause Hypotension?
SACUBITRIL\VALSARTAN (11,718)
AMLODIPINE (6,504)
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (4,694)
FUROSEMIDE (4,468)
TREPROSTINIL (4,412)
METOPROLOL (3,213)
RITUXIMAB (3,208)
METFORMIN (3,116)
LENALIDOMIDE (2,920)
ACETAMINOPHEN (2,817)
Which TISAGENLECLEUCEL Alternatives Have Lower Hypotension Risk?
TISAGENLECLEUCEL vs TISLELIZUMAB
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN-TFTV
TISAGENLECLEUCEL vs TITANIUM DIOXIDE\ZINC
TISAGENLECLEUCEL vs TIVICAY