Does TISAGENLECLEUCEL Cause Leukopenia? 24 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 24 reports of Leukopenia have been filed in association with TISAGENLECLEUCEL (KYMRIAH). This represents 0.6% of all adverse event reports for TISAGENLECLEUCEL.
24
Reports of Leukopenia with TISAGENLECLEUCEL
0.6%
of all TISAGENLECLEUCEL reports
8
Deaths
13
Hospitalizations
How Dangerous Is Leukopenia From TISAGENLECLEUCEL?
Of the 24 reports, 8 (33.3%) resulted in death, 13 (54.2%) required hospitalization, and 5 (20.8%) were considered life-threatening.
Is Leukopenia Listed in the Official Label?
Yes, Leukopenia is listed as a known adverse reaction in the official FDA drug label for TISAGENLECLEUCEL.
What Other Side Effects Does TISAGENLECLEUCEL Cause?
Cytokine release syndrome (1,660)
Pyrexia (1,030)
Malignant neoplasm progression (582)
Hypotension (425)
Immune effector cell-associated neurotoxicity syndrome (416)
Neurotoxicity (411)
Platelet count decreased (397)
White blood cell count decreased (392)
Hypogammaglobulinaemia (374)
Lymphocyte count decreased (365)
What Other Drugs Cause Leukopenia?
METHOTREXATE (2,694)
CYCLOPHOSPHAMIDE (2,482)
RITUXIMAB (2,191)
CLOZAPINE (2,036)
PREDNISONE (1,725)
DOXORUBICIN (1,696)
PACLITAXEL (1,649)
CARBOPLATIN (1,624)
DEXAMETHASONE (1,542)
MYCOPHENOLATE MOFETIL (1,491)
Which TISAGENLECLEUCEL Alternatives Have Lower Leukopenia Risk?
TISAGENLECLEUCEL vs TISLELIZUMAB
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN-TFTV
TISAGENLECLEUCEL vs TITANIUM DIOXIDE\ZINC
TISAGENLECLEUCEL vs TIVICAY