Does TISAGENLECLEUCEL Cause Neutropenia? 167 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 167 reports of Neutropenia have been filed in association with TISAGENLECLEUCEL (KYMRIAH). This represents 4.0% of all adverse event reports for TISAGENLECLEUCEL.
167
Reports of Neutropenia with TISAGENLECLEUCEL
4.0%
of all TISAGENLECLEUCEL reports
72
Deaths
54
Hospitalizations
How Dangerous Is Neutropenia From TISAGENLECLEUCEL?
Of the 167 reports, 72 (43.1%) resulted in death, 54 (32.3%) required hospitalization, and 55 (32.9%) were considered life-threatening.
Is Neutropenia Listed in the Official Label?
Yes, Neutropenia is listed as a known adverse reaction in the official FDA drug label for TISAGENLECLEUCEL.
What Other Side Effects Does TISAGENLECLEUCEL Cause?
Cytokine release syndrome (1,660)
Pyrexia (1,030)
Malignant neoplasm progression (582)
Hypotension (425)
Immune effector cell-associated neurotoxicity syndrome (416)
Neurotoxicity (411)
Platelet count decreased (397)
White blood cell count decreased (392)
Hypogammaglobulinaemia (374)
Lymphocyte count decreased (365)
What Other Drugs Cause Neutropenia?
CLOZAPINE (18,981)
CYCLOPHOSPHAMIDE (7,352)
LENALIDOMIDE (6,909)
RITUXIMAB (6,607)
PALBOCICLIB (6,423)
DEXAMETHASONE (6,050)
DOXORUBICIN (5,891)
CARBOPLATIN (5,314)
VINCRISTINE (4,982)
PACLITAXEL (4,553)
Which TISAGENLECLEUCEL Alternatives Have Lower Neutropenia Risk?
TISAGENLECLEUCEL vs TISLELIZUMAB
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN-TFTV
TISAGENLECLEUCEL vs TITANIUM DIOXIDE\ZINC
TISAGENLECLEUCEL vs TIVICAY