Does TISAGENLECLEUCEL Cause Thrombocytopenia? 189 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 189 reports of Thrombocytopenia have been filed in association with TISAGENLECLEUCEL (KYMRIAH). This represents 4.5% of all adverse event reports for TISAGENLECLEUCEL.
189
Reports of Thrombocytopenia with TISAGENLECLEUCEL
4.5%
of all TISAGENLECLEUCEL reports
103
Deaths
48
Hospitalizations
How Dangerous Is Thrombocytopenia From TISAGENLECLEUCEL?
Of the 189 reports, 103 (54.5%) resulted in death, 48 (25.4%) required hospitalization, and 65 (34.4%) were considered life-threatening.
Is Thrombocytopenia Listed in the Official Label?
Yes, Thrombocytopenia is listed as a known adverse reaction in the official FDA drug label for TISAGENLECLEUCEL.
What Other Side Effects Does TISAGENLECLEUCEL Cause?
Cytokine release syndrome (1,660)
Pyrexia (1,030)
Malignant neoplasm progression (582)
Hypotension (425)
Immune effector cell-associated neurotoxicity syndrome (416)
Neurotoxicity (411)
Platelet count decreased (397)
White blood cell count decreased (392)
Hypogammaglobulinaemia (374)
Lymphocyte count decreased (365)
What Other Drugs Cause Thrombocytopenia?
DEXAMETHASONE (5,873)
RITUXIMAB (4,810)
CYCLOPHOSPHAMIDE (4,669)
LENALIDOMIDE (4,584)
CARBOPLATIN (4,483)
METHOTREXATE (3,865)
DOXORUBICIN (3,638)
ETOPOSIDE (3,085)
VINCRISTINE (2,940)
OXALIPLATIN (2,886)
Which TISAGENLECLEUCEL Alternatives Have Lower Thrombocytopenia Risk?
TISAGENLECLEUCEL vs TISLELIZUMAB
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN-TFTV
TISAGENLECLEUCEL vs TITANIUM DIOXIDE\ZINC
TISAGENLECLEUCEL vs TIVICAY