Does TOCILIZUMAB Cause Extremity necrosis? 18 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 18 reports of Extremity necrosis have been filed in association with TOCILIZUMAB (Tocilizumab-anoh). This represents 0.0% of all adverse event reports for TOCILIZUMAB.
18
Reports of Extremity necrosis with TOCILIZUMAB
0.0%
of all TOCILIZUMAB reports
1
Deaths
13
Hospitalizations
How Dangerous Is Extremity necrosis From TOCILIZUMAB?
Of the 18 reports, 1 (5.6%) resulted in death, 13 (72.2%) required hospitalization, and 1 (5.6%) were considered life-threatening.
Is Extremity necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOCILIZUMAB. However, 18 reports have been filed with the FAERS database.
What Other Side Effects Does TOCILIZUMAB Cause?
Drug ineffective (32,342)
Rheumatoid arthritis (20,652)
Pain (18,384)
Off label use (18,256)
Arthralgia (15,536)
Joint swelling (14,831)
Fatigue (13,802)
Rash (12,327)
Drug intolerance (11,952)
Contraindicated product administered (11,547)
What Other Drugs Cause Extremity necrosis?
CANAGLIFLOZIN (95)
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (84)
CARBOPLATIN (46)
PEMETREXED (45)
ADALIMUMAB (42)
GEMCITABINE (40)
METHYLPREDNISOLONE (40)
EPINEPHRINE (39)
PEMBROLIZUMAB (37)
NOREPINEPHRINE (34)
Which TOCILIZUMAB Alternatives Have Lower Extremity necrosis Risk?
TOCILIZUMAB vs TOCILIZUMAB-AAZG
TOCILIZUMAB vs TOCOPHEROL
TOCILIZUMAB vs TOFACITINIB
TOCILIZUMAB vs TOFERSEN
TOCILIZUMAB vs TOLNAFTATE