Does TOCILIZUMAB Cause Hypofibrinogenaemia? 121 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 121 reports of Hypofibrinogenaemia have been filed in association with TOCILIZUMAB (Tocilizumab-anoh). This represents 0.1% of all adverse event reports for TOCILIZUMAB.
121
Reports of Hypofibrinogenaemia with TOCILIZUMAB
0.1%
of all TOCILIZUMAB reports
19
Deaths
39
Hospitalizations
How Dangerous Is Hypofibrinogenaemia From TOCILIZUMAB?
Of the 121 reports, 19 (15.7%) resulted in death, 39 (32.2%) required hospitalization, and 3 (2.5%) were considered life-threatening.
Is Hypofibrinogenaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOCILIZUMAB. However, 121 reports have been filed with the FAERS database.
What Other Side Effects Does TOCILIZUMAB Cause?
Drug ineffective (32,342)
Rheumatoid arthritis (20,652)
Pain (18,384)
Off label use (18,256)
Arthralgia (15,536)
Joint swelling (14,831)
Fatigue (13,802)
Rash (12,327)
Drug intolerance (11,952)
Contraindicated product administered (11,547)
What Other Drugs Cause Hypofibrinogenaemia?
METHOTREXATE (297)
PEGASPARGASE (296)
VINCRISTINE (295)
DAUNORUBICIN (186)
CYTARABINE (177)
DEXAMETHASONE (174)
HYDROCORTISONE (126)
PREDNISONE (124)
PREDNISOLONE (117)
TIGECYCLINE (88)
Which TOCILIZUMAB Alternatives Have Lower Hypofibrinogenaemia Risk?
TOCILIZUMAB vs TOCILIZUMAB-AAZG
TOCILIZUMAB vs TOCOPHEROL
TOCILIZUMAB vs TOFACITINIB
TOCILIZUMAB vs TOFERSEN
TOCILIZUMAB vs TOLNAFTATE