Does TOFACITINIB Cause Appendicitis? 86 Reports in FDA Database

Q: Does TOFACITINIB cause Appendicitis?

86 reports of Appendicitis have been filed with the FDA for TOFACITINIB, representing 0.1% of all TOFACITINIB adverse event reports.

Q: How dangerous is Appendicitis from TOFACITINIB?

Of 86 reports, 3 (3.5%) resulted in death and 42 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 86 reports of Appendicitis have been filed in association with TOFACITINIB (XELJANZ XR). This represents 0.1% of all adverse event reports for TOFACITINIB.

Reports of Appendicitis with TOFACITINIB

0.1%

of all TOFACITINIB reports

Deaths

Hospitalizations

How Dangerous Is Appendicitis From TOFACITINIB?

Of the 86 reports, 3 (3.5%) resulted in death, 42 (48.8%) required hospitalization, and 1 (1.2%) were considered life-threatening.

Is Appendicitis Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 86 reports have been filed with the FAERS database.

What Other Side Effects Does TOFACITINIB Cause?

Drug ineffective (30,382) Pain (21,659) Condition aggravated (16,925) Arthralgia (15,640) Fatigue (13,551) Rheumatoid arthritis (12,277) Off label use (11,736) Headache (11,061) Joint swelling (10,686) Malaise (9,040)

What Other Drugs Cause Appendicitis?

ADALIMUMAB (372) METRONIDAZOLE (291) GABAPENTIN (281) ONDANSETRON (278) SIMVASTATIN (270) CEFTRIAXONE (268) HYDROMORPHONE (265) ALBUTEROL (264) ALLOPURINOL (264) LANSOPRAZOLE (263)

Which TOFACITINIB Alternatives Have Lower Appendicitis Risk?

TOFACITINIB vs TOFERSEN TOFACITINIB vs TOLNAFTATE TOFACITINIB vs TOLODODEKIN ALFA TOFACITINIB vs TOLTERODINE TOFACITINIB vs TOLVAPTAN

TOFACITINIB Full Profile All Appendicitis Reports All Drugs Causing Appendicitis TOFACITINIB Demographics