Does TOFACITINIB Cause Clostridium difficile colitis? 80 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 80 reports of Clostridium difficile colitis have been filed in association with TOFACITINIB (XELJANZ XR). This represents 0.1% of all adverse event reports for TOFACITINIB.
80
Reports of Clostridium difficile colitis with TOFACITINIB
0.1%
of all TOFACITINIB reports
7
Deaths
49
Hospitalizations
How Dangerous Is Clostridium difficile colitis From TOFACITINIB?
Of the 80 reports, 7 (8.8%) resulted in death, 49 (61.3%) required hospitalization, and 9 (11.3%) were considered life-threatening.
Is Clostridium difficile colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 80 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Clostridium difficile colitis?
CYCLOPHOSPHAMIDE (717)
PREDNISONE (619)
DEXAMETHASONE (575)
METHOTREXATE (562)
ETOPOSIDE (503)
CYTARABINE (489)
VINCRISTINE (482)
LENALIDOMIDE (388)
METHYLPREDNISOLONE (385)
CIPROFLOXACIN (378)
Which TOFACITINIB Alternatives Have Lower Clostridium difficile colitis Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN